FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons

Netrin-1 induces repulsive axon guidance by binding to the mammalian Unc5 receptor family (Unc5A–Unc5D). Mouse genetic analysis of selected members of the Unc5 family, however, revealed essential functions independent of Netrin-1, suggesting the presence of other ligands. Unc5B was recently shown to...

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Bibliografiske detaljer
Main Authors: Yamagishi, Satoru, Hampel, Falko, Hata, Katsuhiko, del Toro, Daniel, Schwark, Manuela, Kvachnina, Elena, Bastmeyer, Martin, Yamashita, Toshihide, Tarabykin, Victor, Klein, Rüdiger, Egea, Joaquim
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160250/
https://ncbi.nlm.nih.gov/pubmed/21673655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.189
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