Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation

During early mouse development, the anterior visceral endoderm (AVE) secretes inhibitor and activator signals that are essential for establishing the anterior–posterior (AP) axis of the embryo and for restricting mesoderm formation to the posterior epiblast in the primitive streak (PS) region. Here...

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Autors principals: Egea, Joaquim, Erlacher, Christian, Montanez, Eloi, Burtscher, Ingo, Yamagishi, Satoru, Heß, Martin, Hampel, Falko, Sanchez, Rodrigo, Rodriguez-Manzaneque, Maria Teresa, Bösl, Michael R., Fässler, Reinhard, Lickert, Heiko, Klein, Rüdiger
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600762/
https://ncbi.nlm.nih.gov/pubmed/19056886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.486708
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