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Drosophila Homologue of the Rothmund-Thomson Syndrome Gene: Essential Function in DNA Replication During Development
Members of the RecQ family play critical roles in maintaining genome integrity. Mutations in human RecQL4 cause a rare genetic disorder, Rothmund-Thomson syndrome. Transgenic mice experiments showed that the RecQ4 null mutant causes embryonic lethality. Although biochemical evidence suggests that th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2600506/ https://ncbi.nlm.nih.gov/pubmed/18755177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.08.006 |
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