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Drosophila Homologue of the Rothmund-Thomson Syndrome Gene: Essential Function in DNA Replication During Development
Members of the RecQ family play critical roles in maintaining genome integrity. Mutations in human RecQL4 cause a rare genetic disorder, Rothmund-Thomson syndrome. Transgenic mice experiments showed that the RecQ4 null mutant causes embryonic lethality. Although biochemical evidence suggests that th...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2600506/ https://ncbi.nlm.nih.gov/pubmed/18755177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.08.006 |
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