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Inhibitory effect of blocking TGF-β/Smad signal on injury-induced fibrosis of corneal endothelium

PURPOSE: To understand the role of TGF-β related signals in the repair of a corneal endothelium defect and also to evaluate the therapeutic effect of Smad7 gene transfer on injury induced fibrosis of the corneal endothelium in rats. METHODS: (1) Japanese albino rabbits (n=108) were used. Blocks of c...

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Main Authors: Sumioka, Takayoshi, Ikeda, Kazuo, Okada, Yuka, Yamanaka, Osamu, Kitano, Ai, Saika, Shizuya
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2008
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600488/
https://ncbi.nlm.nih.gov/pubmed/19081766
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