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The phylogeny and evolution of deoxyribonuclease II: An enzyme essential for lysosomal DNA degradation

Deoxyribonuclease II (DNase II) is an endonuclease with optimal activity at low pH, localized within the lysosomes of higher eukaryotes. The origin of this enzyme remains in dispute, and its phylogenetic distribution leaves many questions about its subsequent evolutionary history open. Earlier studi...

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Detalhes bibliográficos
Main Authors: Shpak, Max, Kugelman, Jeffrey R., Varela-Ramirez, Armando, Aguilera, Renato J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600486/
https://ncbi.nlm.nih.gov/pubmed/18226927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ympev.2007.11.033
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