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DNase II deficiency impairs innate immune function in Drosophila
DNase II enzymes are highly conserved proteins that are required for the degradation of DNA within phagolysosomes. Engulfment of apoptotic cells and/or bacteria by phagocytic cells requires the function of DNase II to completely destroy ingested DNA. Mutation of the dnase II gene results in an incre...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430755/ https://ncbi.nlm.nih.gov/pubmed/16854402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2006.05.007 |
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