Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement.

The gene coding for protein A (spa) of Staphylococcus aureus 8325-4 has been inactivated by substituting part of the spa coding sequence for a DNA fragment specifying resistance to ethidium bromide. The in vitro-constructed spa::EtBrr substitution mutation was introduced into the S. aureus chromosom...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Patel, A H, Nowlan, P, Weavers, E D, Foster, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3679545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.12.3103-3110.1987
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