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A Quantitative Model of Cortical Spreading Depression Due to Purinergic and Gap-Junction Transmission in Astrocyte Networks

Spreading depression (SD), a propagating wave of electrical silence in the cortex and archicortex, involves depolarization of neurons and astrocytes for ∼1 min, due principally to a large increase in extracellular K(+). SD is accompanied by large increases in extracellular ATP and is blocked by glut...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bennett, Max R., Farnell, Les, Gibson, William G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Biophysical Society 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599846/
https://ncbi.nlm.nih.gov/pubmed/18952785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137190
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