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A Quantitative Model of Cortical Spreading Depression Due to Purinergic and Gap-Junction Transmission in Astrocyte Networks
Spreading depression (SD), a propagating wave of electrical silence in the cortex and archicortex, involves depolarization of neurons and astrocytes for ∼1 min, due principally to a large increase in extracellular K(+). SD is accompanied by large increases in extracellular ATP and is blocked by glut...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2599846/ https://ncbi.nlm.nih.gov/pubmed/18952785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137190 |
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