Dietary Exposure to 2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE-47) Alters Thyroid Status and Thyroid Hormone–Regulated Gene Transcription in the Pituitary and Brain

BACKGROUND: Polybrominated diphenyl ether (PBDE) flame retardants have been implicated as disruptors of the hypothalamic-pituitary-thyroid axis. Animals exposed to PBDEs may show reduced plasma thyroid hormone (TH), but it is not known whether PBDEs impact TH-regulated pathways in target tissues. OB...

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Detalhes bibliográficos
Main Authors: Lema, Sean C., Dickey, Jon T., Schultz, Irvin R., Swanson, Penny
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599765/
https://ncbi.nlm.nih.gov/pubmed/19079722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11570
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