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The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment.

We investigated the immunogenicity and antigenicity of synthetic lipid A and partial structures thereof. Included in the study were compounds which varied in the position of phosphate (1-mono-, 4'-mono-, and 1,4'-bisphosphates) and in the acylation (type, number, and distribution of fatty...

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Detalhes bibliográficos
Main Authors: Brade, L, Brandenburg, K, Kuhn, H M, Kusumoto, S, Macher, I, Rietschel, E T, Brade, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC259954/
https://ncbi.nlm.nih.gov/pubmed/3666956
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