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Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli.

Two recombinant plasmids, pTet11 and pTet18, which express nontoxic protein fragments of tetanus toxin in Escherichia coli, were constructed. pTet11 protein (86 kilodaltons) is a fusion between part of the E. coli trpE protein and 441 amino acids of tetanus fragment C, and pTet18 (63 kilodaltons) co...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Fairweather, N F, Lyness, V A, Maskell, D J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3312002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.11.2541-2545.1987
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