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Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli.

Two recombinant plasmids, pTet11 and pTet18, which express nontoxic protein fragments of tetanus toxin in Escherichia coli, were constructed. pTet11 protein (86 kilodaltons) is a fusion between part of the E. coli trpE protein and 441 amino acids of tetanus fragment C, and pTet18 (63 kilodaltons) co...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Fairweather, N F, Lyness, V A, Maskell, D J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3312002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.11.2541-2545.1987
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