Construction and characterization of a Vi-positive variant of the Salmonella typhi live oral vaccine strain Ty21a.

The viaB locus coding for the Vi antigen of Salmonella typhi Ty2 was cloned on a 40.6-kilobase fragment into the cosmid vector pHC79. The live, oral, attenuated Vi-negative S. typhi Ty21a vaccine strain was transformed with the recombinant cosmid encoding the viaB locus. Homologous recombination of...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Cryz, S J, Fürer, E, Baron, L S, Noon, K F, Rubin, F A, Kopecko, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2807550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.12.3863-3868.1989
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