Construction and characterization of a Vi-positive variant of the Salmonella typhi live oral vaccine strain Ty21a.
The viaB locus coding for the Vi antigen of Salmonella typhi Ty2 was cloned on a 40.6-kilobase fragment into the cosmid vector pHC79. The live, oral, attenuated Vi-negative S. typhi Ty21a vaccine strain was transformed with the recombinant cosmid encoding the viaB locus. Homologous recombination of...
Uloženo v:
| Vydáno v: | Infect Immun |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2807550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.12.3863-3868.1989 |
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