Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: A role in ovarian pathogenesis

High‐resolution array comparative genomic hybridization of 235 serous epithelial ovarian cancers demonstrated a regional increase at 3q26.2 encompassing SnoN/SkiL, a coregulator of SMAD/TGFβ signaling. SnoN RNA transcripts were elevated in ∼80% of advanced stage serous epithelial ovarian cancers. In...

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Detalhes bibliográficos
Main Authors: Nanjundan, Meera, Cheng, Kwai Wa, Zhang, Fan, Lahad, John, Kuo, Wen-Lin, Schmandt, Rosemarie, Smith-McCune, Karen, Fishman, David, Gray, Joe W., Mills, Gordon B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2008
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598416/
https://ncbi.nlm.nih.gov/pubmed/19383336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2008.05.001
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