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SnoN/SkiL Expression is Modulated via Arsenic Trioxide-Induced Activation of the PI3K/AKT Pathway in Ovarian Cancer Cells
SnoN/SkiL (TGFβ regulator) is dysregulated in ovarian cancer, a disease associated with acquired drug-resistance. Arsenic trioxide (As(2)O(3)used in treating APL) induces SnoN to oppose the apoptotic response in ovarian cancer cells. We now report that As(2)O(3) increases phosphorylation of EGFR/p66...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531974/ https://ncbi.nlm.nih.gov/pubmed/23178716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.11.003 |
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