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A concise synthesis of the cortistatin core
We describe a concise and convergent route to the core matrix of the cortistatin steroidal alkaloids. The salient features of the synthesis are the Snieckus cascade methodology and the Masamune alkylative dearomatization. This chemistry lends itself to a total synthesis of the cortistatins and to th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2598409/ https://ncbi.nlm.nih.gov/pubmed/19924219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.09.018 |
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