Insulin‐degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population

The gene for insulin‐degrading enzyme (IDE), which is located at chromosome 10q24, has been previously proposed as a candidate gene for late‐onset Alzheimer's disease (AD) based on its ability to degrade amyloid β‐protein. Genotyping of single nucleotide polymorphisms (SNPs) in the IDE gene in...

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Autori principali: Vepsäläinen, Saila, Parkinson, Michele, Helisalmi, Seppo, Mannermaa, Arto, Soininen, Hilkka, Tanzi, Rudolph E, Bertram, Lars, Hiltunen, Mikko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
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Letter to JMG
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597950/
https://ncbi.nlm.nih.gov/pubmed/17496198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.048470
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