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Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening
BACKGROUND: The identification of BRCA1 and BRCA2 mutations in familial breast cancer kindreds allows genetic testing of at‐risk relatives. Those who test negative are usually reassured and additional breast cancer surveillance is discontinued. However, we postulated that in high‐risk families, such...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597903/ https://ncbi.nlm.nih.gov/pubmed/17079251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.043091 |
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