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Diastereoselective Synthesis of a Highly Substituted cis-Decahydroquinoline via a Knoevenagel Condensation

A diastereoselective approach to 3,7,8-trisubstituted cis-decahydroquinolines is described. This ring system forms the core of rings B and E of the norditerpenoid alkaloid methyllycaconitine. This approach starts with a known disubsituted cyclohexene. The remaining carbons are attached via a Knoeven...

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Détails bibliographiques
Auteurs principaux: Huang, Junfeng, Bergmeier, Stephen C.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597876/
https://ncbi.nlm.nih.gov/pubmed/19572008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.04.073
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