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The first transannular [4+3] cycloaddition reaction: synthesis of the ABCD ring structure of cortistatins

A 14-membered macrocycle with an allene and a furan strategically located at across the ring from each other is synthesized using an allene ring closing metathesis reaction. Upon treatment of the macrocycle with a catalytic amount of Pd(OAc)(2) and other additives, the first transannular [4+3] cyclo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Craft, Derek T., Gung, Benjamin W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597840/
https://ncbi.nlm.nih.gov/pubmed/19812680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.07.155
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