Loading...
Metalated Nitriles: Stereodivergent Cation-Controlled Cyclizations1
Stereodivergent cyclizations of γ-hydroxy cyclohexanecarbonitriles are controlled simply through judicious choice of cation in the alkylmetal base. Deprotonating a series of cyclic γ-hydroxy nitriles with i-PrMgBr generates C-magnesiated nitriles that cyclize under stereoelectronic control to cis-fu...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597827/ https://ncbi.nlm.nih.gov/pubmed/19657380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.05.110 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|