Behavioral responses of dopamine β-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action

Modafinil is approved for use in the treatment of excessive daytime sleepiness. The precise mechanism of modafinil action has not been elucidated, although both dopamine (DA) and norepinephrine (NE) systems have been implicated. To explore the roles of DA and NE in the mechanism of modafinil-induced...

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Autores principales: Mitchell, Heather A., Bogenpohl, James W., Liles, L. Cameron, Epstein, Michael P., Bozyczko-Coyne, Donna, Williams, Michael, Weinshenker, David
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597705/
https://ncbi.nlm.nih.gov/pubmed/18703079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.07.014
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