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Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

BACKGROUND: Defects in the small intestinal epithelial barrier have been associated with inflammatory bowel disease but their role in the causation of disease is still a matter of debate. In some models of disease increased permeability appears to be a very early event. The interleukin 10 (IL10) gen...

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Главные авторы: Arrieta, M C, Madsen, K, Doyle, J, Meddings, J
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597688/
https://ncbi.nlm.nih.gov/pubmed/18829978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2008.150888
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