Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers

Phosphoinositide 3-OH kinases (PI3Ks) are a group of major intracellular signaling molecules. In our previous study, we found that inhibition of PI3K activity suppressed the androgen receptor (AR)-mediated gene expression in prostate cancer cells. The AR has been considered as a critical determinant...

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Autors principals: Zhu, Q, Youn, H, Tang, J, Tawfik, O, Dennis, K, Terranova, PF, Du, J, Raynal, P, Thrasher, JB, Li, B
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597686/
https://ncbi.nlm.nih.gov/pubmed/18372911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.91
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