Specific microbiota direct the differentiation of Th17 cells in the mucosa of the small intestine

IL-17-producing T-helper cells (Th17) are potent effectors of inflammation, but little is known about the requirements for their differentiation in vivo at steady state. We found that specific commensal microbiota are required for Th17 cell differentiation in the lamina propria (LP) of the small int...

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Bibliografiske detaljer
Main Authors: Ivanov, Ivaylo Ivanov, de Llanos Frutos, Rosa, Manel, Nicolas, Yoshinaga, Keiji, Rifkin, Daniel B., Sartor, R. Balfour, Finlay, B. Brett, Littman, Dan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597589/
https://ncbi.nlm.nih.gov/pubmed/18854238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.09.009
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