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Synthesis and Characterization of Novel lacZ Gene Reporter Molecules: Detection of β-Galactosidase Activity Using (19)F NMR of Polyglycosylated Fluorinated Vitamin B(6)

Gene therapy has emerged as a promising strategy for treatment of various diseases. However, widespread implementation is hampered by difficulties in assessing the success of transfection, in particular, the spatial extent of expression in the target tissue and the longevity of expression. Thus, the...

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Detalhes bibliográficos
Main Authors: Yu, Jianxin, Mason, Ralph P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597532/
https://ncbi.nlm.nih.gov/pubmed/16539386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm051049o
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