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Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs
The peptidic anti-HIV drug T20 (Fuzeon) and its analog C34 share a common heptad repeat (HR) sequence, but they have different functional domains, i.e., pocket- and lipid-binding domains (PBD and LBD, respectively). We hypothesize that novel anti-HIV peptides may be designed by using artificial sequ...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Inc.
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597519/ https://ncbi.nlm.nih.gov/pubmed/18682248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.134 |
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