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Mechanistic studies on the mononuclear Zn(II)-containing metallo-β-lactamase ImiS from Aeromonas sobria
In an effort to understand the reaction mechanism of a B2 metallo-β-lactamase, steady-state and pre-steady state kinetic and rapid-freeze quench EPR studies were conducted on ImiS and its reaction with imipenem and meropenem. pH Dependence studies revealed no inflection points in the pH range of 5.0...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597473/ https://ncbi.nlm.nih.gov/pubmed/16939225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060893t |
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