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The Role of Hypothalamic Mammalian Target of Rapamycin Complex 1 Signaling in Diet-Induced Obesity

The mammalian target of rapamycin (mTOR) kinase is a key regulator of several cellular functions, including cell growth and differentiation. Because hypothalamic mTOR complex 1 (mTORC1) signaling has been implicated as a target of leptin in the regulation of energy balance, we investigated its role...

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Détails bibliographiques
Auteurs principaux: Cota, Daniela, Matter, Emily K., Woods, Stephen C., Seeley, Randy J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597379/
https://ncbi.nlm.nih.gov/pubmed/18614690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1389-08.2008
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