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SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial Metabolism
Tumors frequently develop resistance to cisplatin, a platinum drug used as a cornerstone of present day chemotherapy regimens, significantly decreasing its usefulness in the clinic. Although it is known that cisplatin-resistant (CP-r) cancer cells commonly grow more slowly and exhibit reduced uptake...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597364/ https://ncbi.nlm.nih.gov/pubmed/18723829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-2130 |
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