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Oxidative Inactivation of Key Mitochondrial Proteins Leads to Dysfunction and Injury in Hepatic Ischemia Reperfusion

BACKGROUND & AIMS: Ischemia-reperfusion (I/R) is a major mechanism of liver injury following hepatic surgery or transplantation. Despite numerous reports on the role of oxidative/nitrosative stress and mitochondrial dysfunction in hepatic I/R injury, the proteins that are oxidatively-modified du...

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Hlavní autoři: MOON, KWAN-HOON, HOOD, BRIAN L., MUKHOPADHYAY, PARTHA, MOHANRAJ, RAJESH, ABDELMEGEED, MOHAMED A., KWON, YONG-IL, CONRADS, THOMAS P., VEENSTRA, TIMOTHY D., SONG, BYOUNG-JOON, PACHER, PAL
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597302/
https://ncbi.nlm.nih.gov/pubmed/18778711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.06.048
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