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Pivotal Advance: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis

In this study, we have investigated the role of the cannabinoid CB(2) (CB(2)) receptor in an in vivo mouse model of hepatic ischemia/reperfusion (I/R) injury. In addition, we have assessed the role of the CB(2) receptor in TNF-α-induced ICAM-1 and VCAM-1 expression in human liver sinusoidal endothel...

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Detalhes bibliográficos
Main Authors: Rajesh, Mohanraj, Pan, Hao, Mukhopadhyay, Partha, Bátkai, Sándor, Osei-Hyiaman, Douglas, Haskó, György, Liaudet, Lucas, Gao, Bin, Pacher, Pál
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225476/
https://ncbi.nlm.nih.gov/pubmed/17652447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0307180
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