Activation of the endocannabinoid system by organophosphorus nerve agents

Δ(9)-Tetrahydrocannabinol (THC), the psychoactive ingredient of marijuana, exhibits useful medicinal properties, but also undesirable side-effects. The brain receptor for THC, CB(1), is also activated by the endogenous cannabinoids anandamide and 2-arachidonylglycerol (2-AG). Augmentation of endocan...

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Bibliographic Details
Main Authors: Nomura, Daniel K., Blankman, Jacqueline L., Simon, Gabriel M., Fujioka, Kazutoshi, Issa, Roger S., Ward, Anna M., Cravatt, Benjamin F., Casida, John E.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597283/
https://ncbi.nlm.nih.gov/pubmed/18438404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.86
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