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CGRP blockers in migraine therapy: where do they act?

Calcitonin gene-related peptide (CGRP) is expressed throughout the CNS and peripheral nervous system, consistent with control of vasodilatation, nociception, motor function, secretion and olfaction. αCGRP is prominently localized in primary afferent C and Aδ fibres of spinal and trigeminal ganglia....

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Autor principal: Edvinsson, L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597260/
https://ncbi.nlm.nih.gov/pubmed/18776915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.346
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