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Calcitonin gene-related peptide (CGRP) antagonists: blockers of neuronal transmission in migraine

The neuropeptide calcitonin gene-related peptide (CGRP) is a potent vasodilator that is contained in and released from sensory nerves. CGRP has been implicated in migraine, and the nonpeptide CGRP antagonist BIBN4096BS has been shown to be effective in clinical trials in migraine. To date, it has be...

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Autor principal: Brain, Susan D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575173/
https://ncbi.nlm.nih.gov/pubmed/15237096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705806
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