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Calcitonin gene-related peptide (CGRP) antagonists: blockers of neuronal transmission in migraine
The neuropeptide calcitonin gene-related peptide (CGRP) is a potent vasodilator that is contained in and released from sensory nerves. CGRP has been implicated in migraine, and the nonpeptide CGRP antagonist BIBN4096BS has been shown to be effective in clinical trials in migraine. To date, it has be...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1575173/ https://ncbi.nlm.nih.gov/pubmed/15237096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705806 |
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