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The calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS blocks CGRP and adrenomedullin vasoactive responses in the microvasculature

1. Calcitonin gene-related peptide (CGRP) is a potent microvascular dilator neuropeptide that is considered to play an essential role in neurogenic vasodilatation and in maintaining functional integrity in peripheral tissues. 2. We have examined the effect of the nonpeptide CGRP antagonist BIBN4096B...

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Autors principals: Grant, A D, Tam, C W, Lazar, Z, Shih, M K, Brain, S D
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575178/
https://ncbi.nlm.nih.gov/pubmed/15237099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705824
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