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‘Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors

BACKGROUND AND PURPOSE: The endocannabinoid N-arachidonoylethanolamide (anandamide) is co-synthesized with other N-acylethanolamides, namely N-palmitoylethanolamide (PEA) and N-oleoylethanolamide (OEA), which have been shown to potentiate anandamide responses (so-called ‘entourage effects') in...

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Detalhes bibliográficos
Main Authors: Ho, W-SV, Barrett, D A, Randall, M D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597234/
https://ncbi.nlm.nih.gov/pubmed/18695637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.324
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