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MASS SPECTROMETRY OF THE FIFTH NUCLEOSIDE: A REVIEW OF THE IDENTIFICATION OF PSEUDOURIDINE IN NUCLEIC ACIDS
Pseudouridine, the so-called fifth nucleoside due to its ubiquitous presence in RNAs, remains among the most challenging modified nucleosides to characterize. As an isomer of the major nucleoside uridine, pseudouridine cannot be detected by standard reverse-transcriptase based DNA sequencing or RNas...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597214/ https://ncbi.nlm.nih.gov/pubmed/18620915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2008.06.027 |
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