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MASS SPECTROMETRY OF THE FIFTH NUCLEOSIDE: A REVIEW OF THE IDENTIFICATION OF PSEUDOURIDINE IN NUCLEIC ACIDS

Pseudouridine, the so-called fifth nucleoside due to its ubiquitous presence in RNAs, remains among the most challenging modified nucleosides to characterize. As an isomer of the major nucleoside uridine, pseudouridine cannot be detected by standard reverse-transcriptase based DNA sequencing or RNas...

詳細記述

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書誌詳細
主要な著者: Durairaj, Anita, Limbach, Patrick A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597214/
https://ncbi.nlm.nih.gov/pubmed/18620915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2008.06.027
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