Modulation of Macrophage Activation State Protects Tissue from Necrosis during Critical Limb Ischemia in Thrombospondin-1-Deficient Mice

BACKGROUND: Macrophages, key regulators of healing/regeneration processes, strongly infiltrate ischemic tissues from patients suffering from critical limb ischemia (CLI). However pro-inflammatory markers correlate with disease progression and risk of amputation, suggesting that modulating macrophage...

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Hlavní autoři: Bréchot, Nicolas, Gomez, Elisa, Bignon, Marine, Khallou-Laschet, Jamila, Dussiot, Michael, Cazes, Aurélie, Alanio-Bréchot, Cécile, Durand, Mélanie, Philippe, Josette, Silvestre, Jean-Sébastien, Van Rooijen, Nico, Corvol, Pierre, Nicoletti, Antonino, Chazaud, Bénédicte, Germain, Stéphane
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597179/
https://ncbi.nlm.nih.gov/pubmed/19079608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003950
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