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Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3β Inactivation
Glycogen synthase kinase 3β (GSK3β) is involved in metabolism, neurodegeneration, and cancer. Inhibition of GSK3β activity is the primary mechanism that regulates this widely expressed active kinase. Although the protein kinase Akt inhibits GSK3β by phosphorylation at the N terminus, preventing Akt-...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597039/ https://ncbi.nlm.nih.gov/pubmed/18451303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1156037 |
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