Tumor necrosis factor (cachectin) mediates induction of cachexia by cord factor from mycobacteria.
The mechanism by which cord factor (CF), a toxic glycolipid from mycobacteria, induces cachexia was studied in BALB/c mice. Body weight was markedly reduced 48 h after CF administration; the animals became severely wasted and exhibited hypertriglyceridemia, hypoglycemia, and high levels of tumor nec...
Guardat en:
| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259702/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3053451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.12.3067-3071.1988 |
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