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approximated encodes a DHHC palmitoyltransferase that regulates Fat signaling and the subcellular localization and activity of Dachs

Signaling via the large protocadherin Fat (Ft), regulated in part by its binding partner Dachsous (Ds) and the Golgi-resident kinase Four-jointed (Fj), is required for a variety of developmental functions in Drosophila. Ft and, to a lesser extent, Ds, suppress overgrowth of the imaginal discs from w...

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Autori principali: Matakatsu, Hitoshi, Blair, Seth S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597019/
https://ncbi.nlm.nih.gov/pubmed/18804377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.07.067
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