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Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif

Parasites of the Leishmania genus can rapidly alter several macrophage (MØ) signalling pathways in order to tame down the innate immune response and inflammation, therefore favouring their survival and propagation within their mammalian host. Having recently reported that Leishmania and bacterial LP...

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Detalhes bibliográficos
Main Authors: Abu-Dayyeh, Issa, Shio, Marina Tiemi, Sato, Shintaro, Akira, Shizuo, Cousineau, Benoit, Olivier, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596967/
https://ncbi.nlm.nih.gov/pubmed/19104650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000305
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