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Multilocus LD Measure and Tagging SNP Selection with Generalized Mutual Information
Linkage disequilibrium (LD) plays a central role in fine mapping of disease genes and, more recently, in characterizing haplotype blocks. Classical LD measures, such as D′ and r(2), are frequently used to quantify relationship between two loci. A pairwise “distance” matrix among a set of loci can be...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596944/ https://ncbi.nlm.nih.gov/pubmed/16173096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20092 |
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