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Multilocus LD Measure and Tagging SNP Selection with Generalized Mutual Information

Linkage disequilibrium (LD) plays a central role in fine mapping of disease genes and, more recently, in characterizing haplotype blocks. Classical LD measures, such as D′ and r(2), are frequently used to quantify relationship between two loci. A pairwise “distance” matrix among a set of loci can be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zhenqiu, Lin, Shili
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596944/
https://ncbi.nlm.nih.gov/pubmed/16173096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20092
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