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Structure of an isolated unglycosylated antibody C(H)2 domain

The C(H)2 (C(H)3 for IgM and IgE) domain of an antibody plays an important role in mediating effector functions and preserving antibody stability. It is the only domain in human immunoglobulins (Igs) which is involved in weak interchain protein–protein interactions with another C(H)2 domain solely t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prabakaran, Ponraj, Vu, Bang K., Gan, Jianhua, Feng, Yang, Dimitrov, Dimiter S., Ji, Xinhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596763/
https://ncbi.nlm.nih.gov/pubmed/18931413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444908025274
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